Actually sport it is a narrative
QuoteScientists from the University of Minnesota say they have created the first-ever synthetic cell built entirely from scratch, and seen it go through an entire 'life' cycle – including reproduction.
"This is the most fascinating and important thing I've ever done in my work, and the realization that it's actually happening was rather slow to sink in," synthetic biologist Kate Adamala, a co-lead on the project told ScienceAlert.
"We've replicated in chemistry what only used to be possible in biology: the complete set of behaviors of a cell. It proves that the most fundamental functions of life, like growth and replication, do not need a mysterious magical spark," she says.
The project is called SpudCell, and it has a genome of just 90 kilobase pairs (kbp). For comparison, the human genome is about 3 million kpb, and biologists previously assumed that a living cell would require at least 113 kpb of genetic data to function properly.
According to Adamala and her colleagues, SpudCell appears to stretch these limits, though their research is yet to be formally published and has not been peer-reviewed.
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QuoteAbstract:
Cells are the fundamental unit of life. Yet there is no natural cell for which all its life-essential functions are understood.
Here we demonstrate a complete cell cycle for a synthetic cell undergoing selection, with genome replication, growth, resource acquisition via feeding, and genetically encoded division. The cell is encoded via a 90kb genome that includes functions needed for resource uptake, transcription, translation, growth, genome replication, and division.
The resulting synthetic cell is sufficiently encouraging to support routinization of synthetic cell engineering workflows, and will ultimately underlie diverse applications across all of biotechnology.