Read The Beginning of Infinity by David Deutsch.
His premise is that we create knowledge by developing what he calls good explanations.
Through conjecture, criticism, and testing, our explanations get better and better, but never reach a final truth. Our knowledge will always be imperfect. We are always at the beginning of infinity....
-ever closer approximation
-ever higher resolution
for intent and purpose on the day it does suffice
essential though is the assurance that it is verifiable, corresponding and attested, communal "make believe"
as good old Soc put it, know that you know nothing, possibly because there may be nothing to be known apart from nothingness